Salmon DNA Treatment: The Next Generation of Skin Rejuvenation
What is Salmon DNA Treatment?
Salmon DNA treatment, also known as Polynucleotide (PN) Therapy or PDRN (Polydeoxyribonucleotide) Therapy, is an advanced regenerative skin treatment designed to repair, hydrate, and rejuvenate the skin from within.
Derived from highly purified salmon DNA, these injectable skin boosters stimulate the skin’s natural healing processes, improve cellular repair, increase collagen production, and enhance overall skin quality. Salmon DNA has a molecular structure remarkably similar to human DNA, making it highly biocompatible and safe for aesthetic treatments.
Unlike traditional dermal fillers that add volume, Salmon DNA treatments focus on improving skin health, texture, elasticity, and hydration at a cellular level.
How Does Salmon DNA Work?
Once injected into the skin, Salmon DNA helps:
- Stimulate collagen and elastin production
- Improve skin hydration
- Repair damaged skin cells
- Reduce inflammation
- Enhance skin elasticity
- Improve skin texture and tone
- Support tissue regeneration and wound healing
- Reduce fine lines and early signs of aging
The result is healthier, firmer, brighter, and more youthful-looking skin that continues to improve over time.

Who Is a Good Candidate?
Salmon DNA treatment is suitable for both men and women who wish to improve skin quality without surgery or significant downtime.
Ideal candidates include individuals who have:
- Dry or dehydrated skin
- Fine lines and wrinkles
- Dull or tired-looking skin
- Sun-damaged skin
- Early signs of aging
- Acne scars
- Enlarged pores
- Thin or fragile skin
- Dark circles under the eyes
- Loss of skin elasticity
- Crepey skin on the neck or hands
The treatment is suitable for younger patients seeking prevention as well as mature patients looking to restore skin quality and firmness.
Different Types of Salmon DNA Treatments
Several formulations are available depending on the treatment area and patient concerns.
1. Rejuran Healer
One of the most well-known Polynucleotide treatments.
Best for:
- Overall facial rejuvenation
- Fine lines
- Skin texture improvement
- Acne scars
- Pore refinement
2. Rejuran I (Under-Eye)
Specifically formulated for the delicate eye area.
Best for:
- Dark circles
- Fine lines around the eyes
- Crepey under-eye skin
- Skin thinning
3. Rejuran S
Designed for scar treatment.
Best for:
- Acne scars
- Surgical scars
- Textural irregularities
4. Vitaran / PN Skin Boosters
Advanced Polynucleotide skin boosters used for intensive hydration and regeneration.
Best for:
- Skin repair
- Hydration
- Skin quality improvement
- Prevention of aging
Areas That Can Be Treated
Salmon DNA is extremely versatile and can be used on multiple areas of the body.
Face
The most common treatment area.
Benefits:
- Improved hydration
- Better skin texture
- Increased firmness
- Reduced fine lines
- Enhanced glow
Under Eyes
Excellent for rejuvenating the delicate eye area.
Benefits:
- Reduced dark circles
- Improved skin thickness
- Smoother fine lines
- Brighter appearance
Neck
The neck often shows signs of aging earlier than the face.
Benefits:
- Improved elasticity
- Reduction in crepey skin
- Enhanced firmness
Décolletage (Chest)
Benefits:
- Improved texture
- Reduction of sun damage
- Increased hydration
Hands
Benefits:
- Skin rejuvenation
- Improved skin quality
- More youthful appearance
Acne Scar Areas
Benefits:
- Improved skin regeneration
- Smoother skin texture
- Better scar appearance
How Often Is Salmon DNA Recommended?
Treatment protocols vary depending on the patient’s skin condition and goals.
Initial Treatment Phase
Most patients benefit from:
3 sessions performed 3–4 weeks apart
This allows gradual stimulation of collagen production and tissue regeneration.
Maintenance Phase
After completing the initial course, maintenance sessions are typically recommended every:
6–12 months
Patients with significant skin damage or advanced aging concerns may benefit from more frequent treatments as advised by their practitioner.
What Results Can You Expect?
Many patients notice improved hydration and skin radiance within the first few weeks.
Optimal results typically develop gradually over several months as collagen production increases and cellular repair continues.
Expected improvements include:
- Brighter complexion
- Smoother skin texture
- Improved elasticity
- Better hydration
- Reduced fine lines
- Healthier-looking skin
- Enhanced skin quality overall
Because Salmon DNA works through regeneration rather than simply adding volume, the results appear natural and progressive.

Can Salmon DNA Be Combined with Other Treatments?
Yes. Salmon DNA treatments can be combined with:
- Hydrafacial
- Microneedling
- Morpheus8
- PRP (Platelet-Rich Plasma)
- Skin boosters
- Laser treatments
- HIFU and Sofwave
- Medical-grade skincare
Combining treatments often enhances overall rejuvenation results and provides a more comprehensive anti-aging approach.

Why Choose Salmon DNA Treatment?
Salmon DNA has become one of the most sought-after regenerative aesthetic treatments worldwide because it focuses on improving skin health from within rather than simply masking signs of aging.
For patients seeking natural-looking rejuvenation, improved skin quality, enhanced hydration, and long-term skin health, Salmon DNA treatment offers a scientifically advanced solution with minimal downtime and impressive results.
At The Practice Polyclinic, our experienced aesthetic team tailors every treatment plan to your individual skin concerns and goals, helping you achieve healthier, firmer, and more radiant skin through evidence-based regenerative medicine.

FAQ
What is Salmon DNA Treatment?
A regenerative skin booster that improves hydration, collagen production, and overall skin quality.
What areas can be treated?
Face, under-eyes, neck, hands, décolletage, and acne scars.
How many sessions are recommended?
Typically 3 sessions, 3–4 weeks apart, followed by maintenance every 6–12 months.
Is there any downtime?
Minimal downtime. Mild redness or swelling may occur for 24–48 hours.
When will I see results?
Most patients notice improved skin hydration and glow within a few weeks.
Can it be combined with other treatments?
Yes, it works well with PRP, Morpheus8, Hydrafacial, laser treatments, and other skin boosters.
Who is a suitable candidate?
Anyone looking to improve skin hydration, texture, elasticity, fine lines, or acne scars.
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