Education & Qualifications

2015

FRCP (UK)

Royal College of Physicians, London

2010

CCT in Gastroenterology & General (Internal) Medicine

2010

PhD

University College London

2001

MRCP (UK)

Royal College of Physicians, London

1997

MB BS (London)

Royal Free Hospital & School of Medicine

1994

BSc (Hons) Immunopathology & Basic Medical Sciences

Royal Free Hospital & School of Medicine

Work History

Jul 11- present

Consultant Physician & Gastroenterologist

UCL Hospitals NHS Foundation Trust, London

Honorary Associate Professor, University College London

Mar 02 – Jun 11

Specialist Registrar training in Gastroenterology & General (Internal) Medicine

North East Thames Rotation

Membership of Learned Bodies

British Association of Parenteral and Enteral Nutrition

European Society of Parenteral and Enteral Nutrition

British Society of Gastroenterology

European Crohn’s and Colitis Organisation

Royal College of Physicians, London

Grants & Prizes

2005

NPS Pharma Ltd Clinical Research Grant

2007

Chronic Granulomatous Disease Research Trust

2006

National Association for Colitis & Crohn’s Disease

1994

Goldberg Schachmann Award for Intercalated BSc

Publications

T Kumagai, F Rahman, A Smith. The microbiome and radiation-induced bowel injury: evidence for potential mechanistic role in disease pathogenesis. Nutrients 2018

A Miles & METRIC investigators. Magnetic resonance enterography, small bowel ultrasound and colonoscopy to diagnose and stage Crohn’s disease: patient acceptability and perceived burden. Eur Radiol. 2018

S Burden, D Jones, M Gittins, J Ablett, M Taylor, C Moutford, J Tyrell-Price, C Donellan, F Leslie, T Bowling, S Gabe, F Rahman et al. Needs-based quality of life in adults dependent on home parenteral nutrition. Clin Nutr. 2018

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Y Wouters, M Theilla, P Singer, S Tribler, P Jeppesen, L Pironi, L Vinter-Jensen, H Rasmussen, F Rahman, G Wanten. Randomised clinical trial: 2% taurolidine versus 0.9% saline locking in patients on home parenteral nutrition. Aliment Pharmacol Ther. 2018
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F Pantoja, K Fragkos, P Patel, N Keane, M Samaan, I Barnova, S DiCaro, S Mehta, F Rahman. Refeeding syndrome in adults receiving total parenteral nutrition: An audit of practice at a tertiary UK centre. Clin Nutr. 2018

SA Taylor & METRIC study investigators. Diagnostic accuracy of magnetic resonance enterography and small bowel ultrasound for the extent and activity of newly diagnosed and relapsed Crohn’s disease (METRIC): a multicentre trial. Lancet Gastroenterol Hepatol. 2018; 3(8): 548-558

N Keane, K Fragkos, P Patel, F Bertsch, S Mehta, S Di Caro, F Rahman. Performance status, prognostic scoring and parenteral nutrition requirements predict survival in patients with advanced cancer receiving home parenteral nutrition. Nutr Cancer. 2018; 70(1): 73-82

MA Samaan, D de Jong, S Sahami, S Morgan, K Fragkos, S Subramaniam, K Kok, J Makanyanga, I Barnova, H Saravanapavan, I Parisi, S Di Caro, R Vega, F Rahman, et al. Incidence and severity of prepouch ileitis: A distinct disease entity or a manifestation of refractory pouchitis? Inflamm Bowel Dis. 2016; 22(3):662-8
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Y Chen , M Ogundare , CM Williams , Y Wang , GW Sewell , PJ Smith , FZ Rahman , et al . Shotgun cholanomics of ileal fluid. Biochimie . 2013; 95 (33): 461 – 63
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GW Sewell, YA Hannun, X Han , G Koster, J Bielawski,,V Goss, PJ Smith, FZ Rahman , et al.. Lipidomic profiling in Crohn’s disease: abnormalities in phosphatidylinositols, with preservation of ceramide, phosphatidylcholine and phosphatidylserine composition . Int J Biochem Cell Biol . 2012 ; 44 (111): 1839 – 46

FZ Rahman , * GW Sewell , * et al.. Defective TNF release from Crohn’s disease macrophages in response to Toll – like receptor activation: relationship to phenotype and genome wide association susceptibility loci. Inflamm Bowel Dis.. 2012 ; 18 (111): 2120 – 7
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B Hayee, A Antonopoulos , EJ Murphy,, FZ Rahman , et al. G6PC3 mutations are associated with a major defect of glycosylation:: a novel mechanism for neutrophil dysfunction. Glycobiology. 2011 ; 21 (77): 914 – 24

DJB Marks, PJ Smith, FZ Rahman , et al.. Cryptogenic colitis due to occult cytomegalovirus infection. Frontline Gastro enterol. 2011 ; 2 : 57 – 62

S Ghosh, FZ Rahman , et al.. Survival following treatment of aortoesophageal fistula with dual esophageal and aortic intervention. Case Reports in Gastroenterol.. 201 1 ; 5(11): 40 – 44

B Hayee, F Z Rahman , et al.. The neutrophil respiratory burst and bacterial digestion in Crohn’s disease. Dig Dis Sci. 2011; 56 (55): 1482 – 88

FZ Rahman , et al.. Henoch Schönlein Purpura complicating adalimumab therapy for Crohn’s disease . World J Gastro intest Pharmacol Ther. 2010; 1 (55) : 119 – 22
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DJB M arks, CR Seymour, GW Sewell, FZ Rahman , et al . Do adaptive or complement immunodeficiencies predispose to inflammatory bowel disease? A critical review.
Inflamm Bowel Dis.. 2010 ; 16 (111): 1984 – 92

B Hayee, FZ Rahman , et al.. Perspective article:: Crohn’s Disease as an Immunodeficiency.
Expert Review of Clinical Immunology 2010 ; 6 (44): 585 – 96
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FZ Rahman ,* AM Smith,,* et al.. Delayed resolution of acute inflammation in ulcerative colitis is associated with elevated cytokine release downstream of TLR4. PLoS One 2010; 5 (33): e9891
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DJB M arks, FZ Rahman , GW Sewell , AW Segal.. Crohn’s disease: an immune deficiency state. Crit Rev Allergy Immunol.. 2010 ; 38 (11): 20 – 31
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CD Palmer,, FZ Rahman , et al .Multiple PMA – induced macrophage PKC signalling abnormalities in Crohn’s disease.. PLoS One 2009 ; 4 (111): e7787
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FZ Rahman , et al.. Impaired macrophage function following bacterial stimulation in chronic granulomatous disease. Immunology 2009;; 128 (22): 253 – 59
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FZ Rahman ,* AM Smith,,* et al.. Disordered macrophage cytokine secretion underlies impaired acute inflammation and bacterial clearance in Crohn’s disease . J Exp Med..2009; 206 (99): 1883 – 97

R Rajkariar, J. Newson, EK Jackson, P Sawmynaden, A Smith, F Z Rahman , MM Yaqoob,, DW Gilroy. Non-resolving inflammation in gp91phox -/- mice,, a model for human Chronic Granulomatous Disease , is associated with lower adenosine and cAMP levels . J Immunol . 2009;; 182 (55): 3262 – 69
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DJB Marks, K Miyagi, FZ Rahman , et al.. Inflammatory bowel disease in CGD reproduces the clinicopathological features of Crohn’s disease.. Am J Gastroenterol.. 200 9 ; 104 (11): 117 – 24

FZ Rahman , DJB Marks,, et al . Phagocyte dysfunction and Inflammatory bowel disease.. Inflamm Bowel Dis.. 2008 ; 14 (110): 1443 – 52

W Rahman, F Z Rahman , et al.. Progression of retinopathy during pregnancy in type 1 diabetes mellitus. Clin Experiment Ophthalmol. 2007 ; 35 (33): 231 – 36

DJ Marks, FZ Rahman , et al.. An exuberant inflammatory response to E.ccoli: implications for the pathogenesis of ulcerative colitis and pyoderma gangrenosum. Gut 2006; 55 (111):
1662 – 63

DJ Marks, M Harbord, R MacAllister, FZ Rahman , et al . Defective acute inflammation in Crohn’s disease: a clinical investigation. Lancet 2006 ; 367 (99511): 668 – 78

S Rahman,, G Bhattee,, W Rahman,, F Z Rahman . INTERESTING CASE: Wegener’s granulomatosis – a cause of eyelid swelling. Br J Oral Maxillofac Surg. 2005 ; 43 (66): 510

W Rahman, FZ Rahman . Giant cell (temporal) arteritis: an overview and update. Surv Ophthalmol.. 2005 ; 50 (55): 415 – 28

FZ Rahman , et al.. Pregnancy outcome in lupus nephropathy. Arch Gynecol Obstet. 2005 ; 271 (33) : 222 – 26

S Rahman,, W Rahman,, F Z Rahman . A case of facial swelling and proptosis. Dent Update. 2004 ; 31 (99): 553 – 54

W Rahman , F Z Rahman . Sudden visual loss in GCA – a brief review of the current treatment. Saudi J Ophthalmol.. 2004; 18 (11): 25 – 27

J Rahman, FZ Rahman , et al.. Obstetric and gynaecologic complications in women with Marfan’s syndrome . J Reprod Med. 2003 ; 48 (99): 723 – 28

A Izmeth, SS Al – Dujaily, F Rahman , DR Osborne. Right pelvic ectopic kidney with pelviureteric obstruction causing contralateral obstruction to kidney and ureter: a novel presentation of pelvic ectopic kidney . BJU Int.. 1999 ; 84 (77): 875 – 7 6